Do Medicinal Herbs Lose Potency When They Bolt?

Charles City, VA(Zone 7a)

I was wondering if medicinal herbs lost their potency once they go to bolt, particularly Feverfew? I know with most culinary herbs they aren't as good once they've flowered. Does anyone know if this also affects the plants medicinal properties?

Thanks!

Millbury, MA(Zone 5a)

This probably won't be much help -- it really depends on the plant. If you want to make a tincture with St. John's Wort, for instance, you need the flowers.

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